Overview

DNA modifying enzymes are important tools for the manipulation of genetic information and have many biomedical, agricultural and industrial applications. The secondary structure of these enzymes, referring to the arrangement of amino acid residues in three-dimensional space, plays a key role in their activity and specificity. Secondary structure analysis of enzymes can provide valuable insights into enzyme function and facilitate the development of more efficient enzymes. Creative Enzymes provides you with a variety of DNA modifying enzyme secondary structure analysis service to meet your scientific research needs.

Algorithm:

• Our secondary structure prediction algorithm uses machine learning techniques to predict the most likely secondary structure of your enzyme sequence, based on sequence comparisons and other features.
• Our approach is based on a feed-forward neural network trained on multiple sequence comparisons and evolutionary information.
• The algorithm we use takes the amino acid sequence of your enzyme as input and outputs a prediction of the secondary structure of each residue, including alpha-helix, beta-helix, coiled coil, and loop.

Sepcific Secondary Structure Analysis Service Approaches We Offer

• Sequence alignment

We use state-of-the-art algorithms to align your enzyme sequence with other related sequences in public databases such as GenBank or UniProt. Sequence alignment is important to identify conserved residues that are critical to enzyme function.

• Secondary structure prediction

Based on the sequence comparison results, we use advanced prediction algorithms such as PSIPRED, JPred or Phyre2 to predict the secondary structure of your enzyme sequence. Secondary structures include alpha-helices, beta-helices, coils and loops.

• Structural analysis

We analyze the predicted secondary structure of your enzyme to identify key features such as hydrogen bonds, disulfide bonds, salt bridges, and hydrophobic interactions. These features are important for stabilizing protein structure and maintaining enzyme activity.

• Functional analysis

We use the results of our structural analysis to interpret the functional consequences of specific mutations or modifications in your enzyme sequence. We can also compare the secondary structure of your enzyme with that of related enzymes to identify potential functional differences.

Service Process

Our Features

• Creative Enzymes has established a proven enzyme technology platform for a variety of applications. We'll help you design the right secondary structure analysis services to aid your scientific research.
• Creative Enzymes is a leading enzyme technology company offering a trusted suite of services and solutions, especially with our extensive experience in DNA modifying enzyme services.

Deliverables

• We will provide you with a detailed list of predicted secondary structures for each residue in your enzyme sequence, including alpha-helices, beta-helices, coils and loops.
• We will interpret the functional consequences of specific mutations or modifications in your enzyme sequence based on the results of our structural analysis.
• We can also compare the secondary structure of your enzyme with that of related enzymes to identify potential differences in function.

Why Choose Us?

Creative Enzymes is a professional DNA modifying enzyme secondary structure analysis services provider supporting a wide range of enzyme services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. We have accumulated years of quintessence in the field of DNA modifying enzyme services, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.