Overview

DNA modifying enzymes are biocatalysts that help an organism accelerate chemical reactions. DNA modifying enzymes can only function under specific pH, pressure and temperature conditions. Each chemical reaction in the body is highly specific and efficient. They also reduce the activation energy required to initiate the reaction, thereby speeding up the response. The enzymes do not change during the chemical reaction and can therefore be used multiple times. Creative Enzymes provides you with a variety of DNA modifying enzyme conjugation with ligand service to meet your scientific research needs.

Classification of Enzyme Modifications

The enzyme modifications are classified as:

i) Cofactor linkage

ii) Attachment of small functional groups such as methyl, acetyl, sulfate and phosphate groups. Different types of reactions can be used.

Overall Solutions

For different modification effects, DNA modifying enzymes are usually bound to ligands. The effect of the modification depends on the nature of the ligand, the degree of modification and the enzyme used. The binding of small molecules usually occurs when some chemical groups covalently add to the amino acid residues of the target enzyme, catalyzed by the enzyme. Such enzyme modifications can be categorized as:

• Custom enzyme conjugation with small molecules.
• Isolation and purification of enzyme conjugates.
• Purified enzymes, activated enzymes and modified enzymes in kit form (HRP, AP, etc.) for various immunoassays.
• Characterization of enzyme conjugates.

We can use different types of reactions. We offer cofactor linkages including biotinylation, phosphopantetheine, lipoic acid linkage and tetrapyrrole/hemoglobin linkage; small functional group linkages including methylation, N-acetylation, phosphorylation, sulfation and hydroxylation.

Advantages

Detection and purification of the desired enzyme

Tracking of enzyme expression, localization,interaction, activity and conformational changesin complicated cellular signaling events

Service Process

Our Features

• We have accumulated many years of essence in the field of DNA modifying enzyme conjugation with ligand service, helping customers to speed up project development and improve the overall success rate of the project.
• At Creative Enzymes, simply let us know your specific project needs. We will suggest the best strategy for you.
• Creative Enzymes has in-depth cooperation with many biology companies and research institutes, and has extensive experience in providing them with high-quality products and services.

Deliverables

• Results raw data
• Data analysis
• Results analysis
• Summary of relevant parameters

Why Choose Us?

Creative Enzymes is a company that provides professional and comprehensive DNA modifying enzyme conjugation with ligand service. We have years of experience to meet your specific project needs. Creative Enzymes can provide you with personalized solutions to help you thrive every step of the way around your interest in your workflow. If you would like to know more about this service, please feel free to contact us.