Background

There are asymmetric secondary conformations in enzyme molecules, such as α-helix, β-fold, β-turn and other steric structures, which make the enzyme molecules absorb left and right circularly polarized light differently, and become elliptically polarized light after the transmission of left and right circularly polarized light, and this phenomenon is called circular dichroism of proteins. Circular dichroism (CD) is an important technique to resolve the secondary and tertiary conformations of optically active molecules (such as proteins, DNA and enzymes) in solution by using their circular dichroism, and is now widely used in the study of macromolecular stereo structure and function and interactions.

Analysis Approaches We Offer

Circular dichroism (CD) is an important technique that uses the circular dichroism of optically active molecules (such as proteins and DNA) in solution to resolve their secondary and tertiary conformations, and is now widely used to study the stereo structure and function of macromolecules and their interactions. Creative Enzymes provides professional circular dichroism technology services.

Our services have the following advantages over traditional methods:

• Short determination time, simplicity and efficiency.
• Requires minimal sample volume and can be measured in dilute solutions.
• No molecular weight or size limitation.
• Highly sensitive to secondary and tertiary structure changes, and able to detect small changes.
• One-stop after sales services.

Sample Requirements

• Enzyme sample concentration >0.5 mg/mL, purity >90%, solid protein amount not less than 200 ug.
• The sample must maintain a certain level of purity does not contain light-absorbing impurities, the solvent must not have absorption interference at the measurement wavelength; the sample can be completely dissolved in the solvent, forming a homogeneous and transparent solution.

Our Features

• We have accumulated many years of essence in the field of circular dichroism analysis service, helping customers to speed up project development and improve the overall success rate of the project.
• At Creative Enzymes, simply let us know your specific project needs. We will suggest the best strategy for you.
• Creative Enzymes has in-depth cooperation with many biology companies and research institutes, and has extensive experience in providing them with high-quality products and services.

Service Process

Deliverables

• Results raw data
• Data analysis
• Results analysis
• Summary of relevant parameters

Why Choose Us?

Creative Enzymes is a professional enzyme service provider, supporting a variety of circular dichroism analysis service. We have years of experience to meet your specific project needs. Creative Enzymes has accumulated years of quintessence in the field of standard circular dichroism analysis service, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.