DNA modifying enzyme subunit aggregation analysis is an important technique for assessing the functional and structural integrity of DNA modifying enzymes. These enzymes play an important role in the manipulation of genetic material, which is essential in biological processes such as DNA replication, repair and recombination. Subunit aggregation analysis methods provide insight into the oligomeric state of enzymes and their dynamic behavior in solution.Creative Enzymes provides reliable and accurate subunit aggregation analysis services that enable researchers to understand the structure-function relationships of DNA-modified enzymes.
Sepecific Aggregation Analysis Service We Offer
Creative Enzymes offers comprehensive DNA modifying enzyme subunit aggregation analysis services, including SEC, DLS, AUC and MALS technologies. We offer solutions that enable researchers to assess the functional and structural properties of DNA modifying enzymes, which can help in the development of new drugs and biotechnology applications:
Size exclusion chromatography (SEC): SEC separates proteins based on hydrodynamic radius.
Dynamic Light Scattering (DLS): DLS measures fluctuations in scattered light caused by Brownian motion.
Analytical Ultracentrifugation (AUC): AUC determines the settling rate of proteins in a centrifugal force field.
Multi-Angle Light Scattering (MALS): MALS calculates the molecular weight of proteins in solution.
When used together, these techniques provide detailed information about the subunit stoichiometry, quaternary structure, and oligomeric state of a protein.
Sample Requirements
We require our clients to submit purified DNA modified enzyme samples for our subunit aggregation analysis service.
The protein should be in solution form with a minimum concentration of 0.1 mg/ml.
The purity of the sample should be greater than 95%, as impurities can interfere with the accuracy of the results.
We also recommend that customers provide information on the composition and pH of the buffers used in the protein purification process.
Applications
Biotechnology Applications: DNA-modifying enzymes are essential in biotechnology, and understanding their subunit aggregation can help optimize their performance.
Structural biology: Subunit aggregation analysis techniques provide insight into the structural details of DNA-modified enzymes, which can help to resolve their crystal structure.
Our Features
Customized solutions: We offer customized solutions to meet the specific needs of our clients.
Customer Satisfaction: Our team works closely with our clients to ensure customer satisfaction.
Competitive pricing: We offer competitive pricing without compromising the quality of our services.
Deliverables
Oligomeric state of DNA modifying enzymes
Four-level structure of DNA modifying enzymes
Dynamic behavior of DNA modifying enzymes in solution
Detailed report outlining the experimental procedures, results, and conclusions.
Custom enzyme design or optimization strategy
Why Choose Us?
Creative Enzymes provides customized solutions that meet the specific needs of our clients, and our team works closely with them to ensure customer satisfaction. Our services have various applications in drug discovery, biotechnological applications, and structural biology. Choose Creative Enzymes for reliable and accurate subunit aggregation analysis services.
