The restriction has the specificity of sequence recognition ability and high activity of biocatalysis. Under certain conditions, nucleic acid molecules can be cleaved, ligated, amplified and modified, and the enzyme has mild reaction conditions and good biocompatibility. Based on these advantages, this tool enzyme is widely used for the analysis and detection of nucleic acids, proteins and small molecules.
Restriction enzyme sequence and structure comparison is of great importance and the plausibility of each step of structure modeling must be checked. Therefore, errors can be accidentally introduced and propagated, model validation and restriction enzyme evaluation are necessary. Restriction enzyme models can be evaluated as a whole and as individual regions. Initially, the folding of the model can be assessed by similarity to the template sequence, or the quality of the model can be assessed using hot plots.
Creative Enzymes can provide modeling services using Ramachandran plots, a visualization method for determining whether the dihedral angles ψ and φ of amino acid residues in a protein structure are within reasonable limits. It can also reflect whether the conformation of the protein is reasonable.
Creative Enzymes offers you the Ramachandran diagram service. Ramachandran diagrams show the phi and psi of all residues in the protein structure, usually glycine and primitive amino acids are removed and treated separately.
Creative Enzymes provides professional sequence and structure comparisons of restriction enzymes that can help you understand the structural aspects of your research on restriction enzymes.
Creative Enzymes is a professional restriction enzyme sequence and structure comparisons provider supporting a wide range of enzyme services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. We have accumulated years of quintessence in the field of restriction enzyme service, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.
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