DNA modifying enzymes play a crucial role in the regulation of s biology, and epigenetic regulation involves the modification of DNA and histones that affect gene expression without altering the underlying DNA sequence. Electrostatic interactions between these enzymes and their substrates or cofactors are critical to their function. Creative Enzymes provides you with a variety of DNA modifying enzymes electrostatic interactions analysis to meet your scientific research needs.
Sepecific Assay Service We Offer
Electrostatic interaction analysis of DNA modifying enzymes can be performed using a variety of techniques, and we offer comprehensive electrostatic interaction analysis services for DNA modifying enzymes to gain insight into their functional roles and regulatory mechanisms. Our services include:
Isothermal Titration Calorimetry (ITC): We perform ITC experiments to measure the amount of heat generated or absorbed by your DNA modifying enzyme when bound to its substrate or cofactor.
Surface Plasmon Resonance (SPR): We perform SPR experiments to measure the binding kinetics and affinity of your DNA modifying enzyme to its substrate or cofactor.
Circular Dichroism (CD): We perform CD spectroscopy to study the secondary and tertiary structure of your DNA modifying enzyme, as well as conformational changes upon binding.
Bioinformatics analysis: We analyze experimental data using state-of-the-art bioinformatics tools to gain a comprehensive understanding of the static interactions between your DNA modifying enzyme and its substrate or cofactor.
Sample requirements
We require a minimum of 1 μg of purified enzyme or cell lysate per assay. We recommend that samples be frozen at -80°C until shipment.
Our Features
High quality and reliable results backed by our extensive experience and stringent quality control measures.
Solutions tailored to your specific study requirements.
Ongoing technical support to ensure successful implementation of the assay in your study.
Competitive pricing and fast turnaround times.
Deliverables
Binding kinetics and affinity of DNA modifying enzymes to their substrates or cofactors.
Heat generated or absorbed during the binding of DNA modifying enzymes to their substrates or cofactors.
Secondary and tertiary structures of DNA modifying enzymes, and conformational changes upon binding.
Perform comprehensive bioinformatics analysis of experimental data, including interpretation of results and recommendations for future research and applications.
Why Choose Us?
Creative Enzymes provides high quality DNA modifying enzymes electrostatic interactions analysis to help researchers measure enzyme activity and identify inhibitors. Our comprehensive services include custom assay design, optimization, validation and data analysis. We use validated and optimized protocols to ensure accurate and reproducible results. Our experienced team of professionals can assist with all aspects of the assay, from experimental design to result interpretation. We are committed to delivering high-quality services that meet our clients' specific needs and exceed their expectations.
