DNA-modifying enzymes play a crucial role in many areas of molecular biology, from genetic engineering to drug discovery. However, the study of these enzymes can be challenging due to their complex structure and function. Crystallization is one of the most important techniques for understanding the structure and function of DNA modifying enzymes, as it allows researchers to observe their molecular structure at atomic resolution.Creative Enzymes provides high quality DNA modifying enzyme crystallization services, utilizing state-of-the-art technology and expertise to provide solutions for research and development.
Sepecific DNA Modifying Enzymes Crystallization Service We Offer
Creative Enzymes offers comprehensive solutions for the crystallization of DNA-modifying enzymes, including screening, optimization and scale-up.
We begin by screening multiple conditions to determine the optimal buffer, pH, precipitant and other additives for efficient and reproducible crystallization.
Once we determine the optimal conditions, we further optimize them to obtain larger, stronger crystals for X-ray crystallography.
Finally, we scale up the crystallization process to produce a sufficient number of crystals for structural analysis.
Service Process
Consultation: We begin by discussing the project requirements and objectives with the client to determine the best method to meet their specific needs.
Sample Preparation: We then request samples of the DNA-modified enzyme to be studied, which can be purified in-house or provided by the client.
Screening: Our team will perform a thorough screening using a variety of techniques to determine the appropriate conditions for crystal formation.
Optimization: Once the optimal conditions are determined, we will further optimize the crystallization conditions to obtain large, high-quality crystals.
Scale-up: After obtaining high quality crystals, we will scale up the process to produce sufficient quantities of crystals for structural analysis.
Structural Analysis: Finally, we will provide our customers with crystal structure data through X-ray crystallography-based analysis.
Our Features
Customizable Solutions: We offer customizable solutions to meet the unique needs of our customers.
Fast turnaround times: Our efficient screening and optimization process ensures fast turnaround times for our customers.
Competitive pricing: We offer competitive pricing without sacrificing quality.
Deliverables
Results raw data
Data analysis
Results analysis
Summary of relevant parameters
A detailed report on the screening, optimization and scaling of the crystallization process, as well as crystal images and diffraction data
Crystal structure data that can be used for further molecular modeling and design
Why Choose Us?
Creative Enzymes is a professional DNA modifying enzyme crystallization service provider supporting a wide range of enzyme services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. We have accumulated years of quintessence in the field of DNA modifying enzyme crystallization service, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.
