Overview

The use of DNA modifying enzyme-drug coupling as a missile to target a specific group of cells has fewer side effects than conventional cancer treatments. The goal is to create a new molecule by combining a drug with anticancer toxin properties with a DNA modifying enzyme, and to create a new molecule that is essentially greater than the sum of its parts by making it more targeted and more cytotoxic. creative Enzymes' biocoupling-based drug discovery and development programs are built on years of experience . Our contract drug development program offers a comprehensive range of biocoupling strategies that can be custom designed and developed to meet your needs.

Overall Solutions

• Cancer drug can be used to conjugate with DNA modifying enzyme for targeted therapeutic are:

Doxorubicin, Epirubicin, Daunorubicin, Idarubicin, Elsamicin A, Actinomycin D, Bleomycin, Mithramycin, Taxol (Paclitaxel), Docetaxel, Tesetaxel, Vincristine, Vinblastine, Navelbine, Etoposie (VP-16), Beacizumab (Avastin), Cisplatin, Carboplatin, Erlotinib, Mitoxantrone, Busulfan, Nitrogen mustards, Uramustine, Chloroambucil, Melphalan, Cyclophophamid, Ifosfamide, Carmustine, Lomustine, Semustine, Procarbazine, Mitomycin, Praziquantel, Irinotecan, Topotecan, Methotrexate, Pemetrexed, lapatinib, Ambroxol, Demecolcine, CCP (3-cyano-2-chloropyridine), Tegafur-uracil, Mercaptopurine Thioguanine, Ara-C (cytarabine), Gemcitabine, Lamivudine, Capecitabine, Nelarabine, Fludarabine, Leustatin, Dacarbazine, Hydroxyurea, Rituximab, Tumor necrosis factor.

• Antibiotic Conjugation

We can provide conjugate antibody, peptide/protein or oligo/nucleic acid with antibiotic such as: Amoxicillin, clenbuterol, ractopamine, chloramphenicol, Salbutamol, Sulfamethazine, Sulfonamide group, Sulfadiazine, Sulfafurazole, Sulformetoxine, Sulfamethoxypyridazine,Sulfaguanidine, Sulfathiodiazole,Sulfamethoxazole, Sulfamethoxypyridazine, Sulfaguanidine, Sulfathiodiazole, Sulphamethoxydiazine, Sulfamonomethoxine, Madribon, Sulfaquinoxaline, Du-6859a, Streptomycin, Gentamycin,Ampicillin, Tetracycline.

• Vitamins Conjugation

Vitamins A, B1, B12, C and D conjugation, biotin can be cross-linked DNA modifying enzyme and other type of macromolecules.

• Other Drug Conjugates

Aspirin, Ibuprofen, Ketoprofen, 5-Azacytidine, methotrexate, Lisinopril, Pravastatin, Memantine Hydrocloride, Propranolol

Service Process

Our Features

• For each custom project, we assign a team of expert chemists and biologists to help our partners define their research path and goals.
• We also provide full assistance in realizing the scientific and business plan, as well as delivering the scientific and business plan.
• Creative Enzymes is a leading enzyme technology company offering a trusted suite of services and solutions, especially with our extensive experience in DNA modifying enzyme conjugation with drug service.

Deliverables

• Results raw data
• Data analysis
• Results analysis
• Summary of relevant parameters

Why Choose Us?

At Creative Enzymes, Our goal is to apply innovative technologies to the production.We offer innovative, flexible and scalable solutions that can meet the needs of our customers. We strive to meet this challenge as a global company that places a high priority on collaborative interactions, rapid delivery of solutions, and providing the highest level of quality. If you would like to know more about this service, please feel free to contact us.