Assay Development

Overview

DNA modifying enzymes, such as DNA methyltransferases (DNMTs) and DNA demethylases (DMRs), play key roles in epigenetic regulation involved in a variety of biological processes. Accurate and sensitive assays for the activity of these enzymes are essential for understanding their function and developing drugs to target them.Creative Enzymes offers a wide range of services for the development of assays for DNA modifying enzymes, including DNMTs and DMRs.

Overall Solutions

  • Creative Enzymes offers comprehensive solutions for the development of assays for DNA-modifying enzymes.
  • Our team of experts can design and optimize assays to meet your specific needs, from screening for potential inhibitor compounds to studying the enzyme's mechanism of action.
  • We also provide customized protocols and technical support to ensure the successful implementation of the assay in your study.

Sepecific Assay Development We Offer

Creative Enzymes has extensive capabilities in the development of DNA modifying enzymes, including assays for DNMTs and DMRs. Our capabilities include, but are not limited to:

  • Development of radiometric assays, fluorometric assays and ELISA-based assays
  • Optimization of substrate and cofactor concentrations
  • Kinetic analysis of enzymes
  • Inhibitor screening

Our Service Process

  • Consultation: We start by discussing your project and requirements to understand your goals and challenges.
  • Assay Design and Optimization: We design and optimize the assay solution that is right for you.
  • Validation and Quality Control: We validate the developed assay and implement stringent quality control measures.
  • Reporting: We provide detailed reports.
  • Technical Support: We provide ongoing technical support to address any questions you may have about assay performance.

Sample Requirements

  • Samples should be of high quality and free of contaminants, e.g., nucleic acids, lipids or salts.
  • We recommend the use of purified enzymes or cell lysates with known protein concentrations. For some applications, we may also require specialized substrates or cofactors.
  • If needed, we can provide guidance on the best way to prepare the sample.

Applications

Our DNA modifying enzyme assay development services are suitable for a variety of applications, including:

Assay Development

Our Features

  • High quality and reliable results backed by our extensive experience and stringent quality control measures.
  • Solutions tailored to your specific study requirements.
  • Ongoing technical support to ensure successful implementation of the assay in your study.
  • Competitive pricing and fast turnaround times.

Deliverables

  • Results raw data
  • Data analysis
  • Results analysis
  • Summary of relevant parameters
  • Comprehensive reports
  • Protocol for the developed assay
  • We also provide customized technical support to ensure successful implementation of the assay in your research.

Why Choose Us?

Creative Enzymes offers comprehensive assay development services for DNA modifying enzymes, including DNMTs and DMRs. Our experienced team provides customized solutions based on your specific needs, ensuring high quality and reliable results. We also provide ongoing technical support to ensure the successful implementation of the assay in your study. If you would like to know more about this service, please feel free to contact us.

Inquiry

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