DNA modifying enzymes are made of amino acids whose identity and position shape function. Bioinformatics provides insights about sequence-function relationships by analyzing in detail protein sequence databases and activity data. It allows to focus the search for improved variants in the portion of sequence space that actually matters. Our services provide comprehensive enzyme discovery, optimization, experimental validation and project management services for pharmaceutical, biotechnology and other sustainable chemical applications.
Creative Enzymes offers one-stop DNA modifying enzyme discovery service that can meet your research needs for restriction enzyme research. Please feel free to contact us to learn about the available systems and how we can support your R&D.
We use a combination of bioinformatics and 3D molecular modeling to identify your best target enzymes in the shortest possible time.
Our multiscale protocol mimics natural directed evolution by combining bioinformatics, molecular modelling and quantum computing to custom design your enzyme, in less than 1 month.
All your computational and experimental needs in one place. Reduce project costs and meet tight deadlines by performing the experimental validation with our trusted partners.
We can increase reaction rates by 30-700% in a single round of evolution testing 10-90 enzyme variants.
We design a highly complementary active site so your enzyme is selective only to your target substrate, particularly useful if you're looking for asymmetric synthesis.
We can increase or reduce specificity to target new substrates of interest for your preferred DNA modifying enzyme.
Creative Enzymes is a professional DNA modifying enzyme service provider supporting a wide range of enzyme services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. We have accumulated years of quintessence in the field of DNA modifying enzyme discovery service, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.
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