DNA is a functionally significant molecule that has evolved to encode and transmit information in multiple dimensions.DNA modifying enzymes are a class of enzymes that cleave, label, extend and ligate DNA substrates. DNA modifying enzymes include DNA glycosylases, DNA methyltransferases, phosphatases, kinases, telomerase, DNA ligases and other enzymes.DNA modifying enzymes play an important role in the regulation of gene expression and are involved in a variety of cellular processes such as DNA repair, cell proliferation, differentiation, aging and apoptosis. DNA modifying enzymes can be used as effective biomarkers for disease diagnosis and as potential targets for anti-cancer therapy and drug screening, and the development of biosensors for efficient detection of DNA modifying enzymes is important for biomedical research, clinical diagnosis and drug discovery.
Creative Enzymes offers methods for the detection of DNA modifying enzymes including gel electrophoresis, radioactive labeling, enzyme-linked immunosorbent assays (ELISA), high-performance liquid chromatography (HPLC), and ratiometric assays, high performance liquid chromatography (HPLC), and colorimetry.
Biosensors are small devices that use biological and biochemical reactions to detect target analytes. Biosensors consist of three main components, namely, a biometric element, a transducer and a signal processing system. The main methods used in the transducer are electrochemical, optical, thermometric, piezoelectric and magnetic. Compared with traditional small molecule detection methods, biosensors have the advantages of low cost, fast response time, portability, and simplicity of operation, making them very suitable for real-time measurements and analysis of complex samples, among others.
Creative Enzymes is a professional DNA modifying enzyme service provider supporting a wide range of enzyme services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. We have accumulated years of quintessence in the field of DNA modifying enzyme detetion service, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.
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