Overview

DNA methylation is a well-known epigenetic modification that typically occurs at the C-5 position of cytosine (C) or the N-6 position of adenine (A) in genomic DNA and plays an important role in a variety of biological processes in both prokaryotes and eukaryotes. Abnormal DNA methylation may alter DNA structure, lead to genomic instability, inactivate tumor suppressor genes, cause transcriptional silencing, and is associated with many types of human diseases (e.g., neurodegenerative diseases and immune system disorders) and cancers (e.g., breast, lung, thyroid, colon, liver, kidney, and cervical cancers). Creative Enzymes provides you with a variety of DNA modifying enzyme service to meet your scientific research needs.

Overall Solutions

• Due to their important functions in establishing and maintaining methylation patterns, DNA MTases have been widely recognized as potential biomarkers for disease development and therapeutic targets for cancer therapy. Therefore, accurate and sensitive detection of multiple DNA MTases is important for biochemical studies and clinical diagnosis of human diseases related to DNA methylation.
• Aggregation-induced emission luminogens (AIEgens) are a new class of biosensing molecules that emit light weakly in the dispersed state and strongly in the aggregated state. Taking advantage of this feature, the synthesis of quenched groups is no longer required, reducing the design procedure. Many AIE bioprobes can be used directly in the diagnosis and treatment of diseases. DNA is an easy to program and control material with high spatial precision. Therefore Creative Enzymes uses this method for DNA methyltransferase detetion service.

Figure 1. Detection schematic. ( Wu J, et al.2020)

Service Process

Our Features

• Creative Enzymes has established a proven enzyme technology platform for a variety of applications. We'll help you design the right DNA methyltransferase detetion service to aid your scientific research.
• Creative Enzymes is a leading enzyme technology company offering a trusted suite of services and solutions, especially with our extensive experience in DNA methyltransferase detetion service.

Deliverables

• Results raw data
• Data analysis
• Results analysis
• Summary of relevant parameters

Why Choose Us?

Creative Enzymes is a professional DNA methyltransferase detetion service provider supporting a wide range of enzyme services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. We have accumulated years of quintessence in the field of DNA methyltransferase detetion service, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.