We use network analysis to predict changes over time in enzyme systems containing DNA-modifying enzymes and other small ligands to explore important biological and pharmaceutical events. Specifically, structures determined experimentally can be improved, enzyme-ligand binding can be evaluated, and biocatalytic processes can be studied. Network analysis is particularly useful in computer-aided drug discovery. It can be used to identify hidden or metastable binding sites, enhance traditional virtual screening methods, and directly predict the binding energy of small molecules.
Overall Solution
Different types of information can be represented in the shape of networks in order to model the cell. The meaning of the nodes and edges used in a network representation depends on the type of data used to build the network.
Different types of data will also produce different general network characteristics in terms of connectivity, complexity and structure, where edges and nodes potentially convey multiple layers of information.
Our services Process
Structural preparation, including DNA modifying enzyme and small molecules, coenzymes, solvent molecules and other structural treatments;
Perform dynamic simulations, including energy optimization, heating, equilibrium phase and production phase;
Analysis trajectory, including RMSD/RMSF, PCA and cluster analysis.
Our Capabilities
Creative Enzymes can provide complex analysis of DNA modifying enzyme and their complexes by using RINs analysis.
We can provide you with estimation about their interdependence and to predict the different properties and functions of individual residues and entire proteins.
We can analyze the chemical and physical properties of the base and the energy of their interaction through the construction of RIN.
We can study the structure and function of DNA modifying enzyme through RINs, which can be applied to drug design in many ways.
Sample Requirements
Our residue interaction network service requires you to provide specific requirements.
Service Process
Our Features
Creative Enzymes has established a proven enzyme technology platform for a variety of applications. We'll help you design the right DNA modifying enzyme signaling networks anlaysis service to aid your scientific research.
Creative Enzymes is a leading enzyme technology company offering a trusted suite of services and solutions, especially with our extensive experience in DNA modifying enzyme signaling networks anlaysis service.
Deliverables
Results raw data
Data analysis
Results analysis
Summary of relevant parameters
Why Choose Us?
Creative Enzymes is a professional DNA modifying enzyme signaling networks anlaysis service provider supporting a wide range of enzyme services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. If you would like to know more about this service, please feel free to contact us.
