Cloning enzyme molecules play a key role in the development of biopharmaceuticals such as monoclonal antibodies, biological vaccines, and diagnostic kits. Creative Enzymes has built a new generation of ab initio sequencing platform based on high resolution mass spectrometry combined with extensive experience in bioinformatics analysis, which enables fast and accurate analysis of monoclonal antibody primary structure, protein sequences and mutations.
1. Full sequence coverage
During the sequence determination process we will select 5 different proteases for enzymatic cleavage and use the complementarity between different enzymatic cleaved peptides to achieve 100% full sequence splicing of the enzyme molecule.
2. Advanced data processing algorithm
We developed our own raw data calculation method for mass spectrometry, using the principle of wide in and narrow out, to achieve accurate identification of protein sequences without missing any valid data information.
3. High precision and accuracy
We use high resolution and high sensitivity mass spectrometers in the sequencing process.
4. Rigorous sequence prediction and strict sequence verification
We will first perform sequence prediction on the sequencing results, and at the same time, we will build a new database with the determined sequences, and analyze the collected mass spectrometry data again by sequence confirmation mode, and we will only provide the customers with the results that match perfectly.
5. Sequencing and mutation analysis
Based on our high-resolution mass spectrometer combined with our rich experience in bioinformatics analysis, we have established a new generation of ab initio sequencing platform for rapid and accurate analysis of protein primary structures.
Creative Enzymes is a company that provides professional and comprehensive cloning enzyme Ab initio sequencing service. We have years of experience to meet your specific project needs. Creative Enzymes can provide you with personalized solutions to help you thrive every step of the way around your interest in your workflow. If you would like to know more about this service, please feel free to contact us.
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