Oxidative DNA damage may be caused by exogenous oxidative stress and reactive oxygen species generated by endogenous aerobic metabolism. The accumulation of oxidative DNA damage and its mutagenic effects can lead to genomic instability, premature aging, and the development of carcinogenesis. DNA glycosylase is an important editing enzyme that maintains genomic stability by removing chemically modified bases that interfere with normal DNA metabolism.
Why is DNA Glycosylase Testing Necessary?
Dysregulation of DNA glycosylases may lead to dysfunction of the damage excision machinery and ultimately lead to a variety of diseases such as immune deficiency, cardiovascular disease, Corkin's syndrome, malnutrition and cancer. Therefore, it is important to establish a sensitive, accurate and simple strategy to detect DNA glycosylase for the monitoring and prognosis of these diseases.
Overall Solutions
Creative Enzymes provides a DNAzyme random walk-based nanostructure for the ultrasensitive detection of uracil-DNA glycosylase.
Creative Enzymes offers gel electrophoresis with fluorescently labeled substrates, but this method has low sensitivity, requires large sample volumes, has low throughput, and is not suitable for quantitative analysis.
Creative Enzymes can improve sensitivity and reduce sample volume by replacing fluorescently labeled substrates with radioisotope labeled substrates.
Creative Enzymes offers high performance liquid chromatography with high qualitative and quantitative capabilities and requires low sample volumes.
Creative Enzymes offers enzyme-linked immunosorbent assays and immunoblotting methods that require specific antibodies bound to proteins.
Service Process
Our Capabilities
Advanced technology platforms: We are equipped with various technology platforms to accuratelyj detect DNA glycosylase.
Accuracy and reproducibility: We provide accurate and detailed results regarding sample purity and homogeneity, thus saving time wasted on bad samples.
Our Features
For each custom project, Creative Enzymes assign a team of expert chemists and biologists to help our partners define their research path and goals.
We also provide full assistance in realizing the scientific and business plan, as well as delivering the scientific and business plan.
Creative Enzymes is a leading enzyme technology company offering a trusted suite of services and solutions, especially with our extensive experience in DNA glycosylase detetion service.
Deliverables
Results raw data
Data analysis
Results analysis
Summary of relevant parameters
Why Choose Us?
Creative Enzymes is a professional enzyme service provider, supporting a variety of DNA glycosylase detetion service. We have years of experience to meet your specific project needs. Creative Enzymes has accumulated years of quintessence in the field of standard DNA glycosylase detetion service, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more about this service, please feel free to contact us.
