Product Description :
eSpCas9 nuclease is a mutant form of Cas9 nuclease. Compared with the wild type Cas9 nuclease, eSpCas9 reduces off-target effects by over 10-fold, while maintaining robust on-target genome editing efficiency. GenScript has developed a eSpCas9-N-NLS nuclease which contains a nuclear localization sequence (NLS) on the N-terminus of the protein to meet all the researchers’ requirements (e.g. in vitro cleavage assay, RNP complex transfection, and micro injection).
Storage Buffer :
10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.4, at 25°C